Bile duct cancer

Also called Cholangiocarcinoma

Bile duct cancer starts in the bile ducts, the small tubes that carry bile from the liver and gallbladder into the bowel. It is rare and mostly affects people over 65. Because early symptoms are vague, it is often found when a blocked duct causes jaundice.

Last updated Nov 9, 2026

What it is

Long-term inflammation of the bile ducts, such as primary sclerosing cholangitis, and some liver conditions increase the risk.

Treatment depends on where the cancer is and how far it has spread, and may include surgery, chemotherapy, targeted treatments, and a stent to relieve a blocked duct.

Common signs

  • Yellowing of the skin and eyes (jaundice)
  • Itchy skin
  • Dark urine and pale stools
  • Tummy pain, weight loss and tiredness

How it is usually diagnosed

  • Blood tests of liver function and tumour markers (CA 19-9)
  • Ultrasound, CT and MRI (MRCP) scans
  • ERCP to see and sample the bile ducts
  • Biopsy

Records worth keeping

Keeping these together makes each appointment easier, especially when you see a new doctor:

  • Liver function and tumour marker results over time
  • Scan and ERCP reports
  • Pathology (biopsy) reports
  • Stent details and treatment plans from the cancer team

Questions to ask your doctor

  • What stage is the cancer, and what are my treatment options?
  • Do I need a stent, and what if it blocks?
  • Who do I contact if I get a fever or new jaundice?

When to get help right away

Call 112 or go to the nearest emergency department if you have:

  • Fever with shivering, especially if you have a stent: this may be a serious infection of the bile ducts

This page is general information. It is not a diagnosis and does not replace a doctor who knows your history. Medfold keeps your records organised; it does not interpret them.

Sources