Rheumatoid arthritis

Also called RA or Inflammatory arthritis

Rheumatoid arthritis is a long-term condition where the immune system attacks the joints, causing pain, swelling and stiffness. It usually affects the hands, feet and wrists, often on both sides of the body. It most often starts between ages 30 and 50 and is more common in women. Smoking raises the risk.

Last updated Nov 9, 2026

What it is

Symptoms often come and go in flare-ups. Without treatment, the joints can become damaged.

Early treatment with disease-modifying medicines, such as methotrexate or biological treatments, can control it. Physiotherapy, occupational therapy and regular blood tests are part of care.

Common signs

  • Painful, swollen joints
  • Stiffness, especially in the morning, lasting more than 30 minutes
  • Joints affected on both sides of the body
  • Tiredness
  • A high temperature or feeling unwell
  • Firm lumps under the skin (nodules)

How it is usually diagnosed

  • Examination of the joints
  • Blood tests for inflammation, rheumatoid factor and anti-CCP antibodies
  • X-rays or ultrasound

Records worth keeping

Keeping these together makes each appointment easier, especially when you see a new doctor:

  • Rheumatology letters
  • Blood test results, including monitoring for medicines
  • X-ray and ultrasound reports
  • Medicine lists

Questions to ask your doctor

  • Which treatment do you recommend first?
  • How often will I need blood tests?
  • What should I do during a flare-up?

When to get help right away

Call 112 or go to the nearest emergency department if you have:

  • A fever, or signs of a serious infection, while on immune-suppressing medicine: get urgent help the same day

This page is general information. It is not a diagnosis and does not replace a doctor who knows your history. Medfold keeps your records organised; it does not interpret them.

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