Reye's syndrome

Also called Reye syndrome

Reye's syndrome is a very rare but serious condition that causes swelling in the liver and brain. It mostly affects children and young people under 20, usually while recovering from a viral infection such as flu or chickenpox. It has been linked to taking aspirin, which is why aspirin should not be given to children under 16 unless a doctor advises it.

Last updated Nov 9, 2026

What it is

It needs emergency treatment in hospital, usually in intensive care, to protect the brain and other organs.

Early treatment improves the chance of recovery, but some people are left with brain damage.

Common signs

  • Repeated vomiting
  • Sleepiness or loss of energy
  • Confusion or unusual behaviour
  • Fast breathing
  • Seizures
  • Loss of consciousness

How it is usually diagnosed

  • Blood tests, including liver tests
  • Brain scans
  • Sometimes a lumbar puncture or liver biopsy

Records worth keeping

Keeping these together makes each appointment easier, especially when you see a new doctor:

  • Blood test results
  • Scan reports
  • Intensive care discharge letters
  • Follow-up letters

Questions to ask your doctor

  • What follow-up will my child need?
  • Which painkillers are safe in future?
  • Are there any lasting effects to watch for?

When to get help right away

Call 112 or go to the nearest emergency department if you have:

  • A child with repeated vomiting, confusion, drowsiness or seizures after a viral illness: call 112

This page is general information. It is not a diagnosis and does not replace a doctor who knows your history. Medfold keeps your records organised; it does not interpret them.

Sources