Non-Hodgkin lymphoma

Also called NHL, Diffuse large B-cell lymphoma, or Follicular lymphoma

Non-Hodgkin lymphoma is a group of cancers that develop in the lymphatic system, part of the immune system. There are many types. Some grow slowly (low-grade), such as follicular lymphoma, and may not need treatment straight away. Others grow quickly (high-grade), such as diffuse large B-cell lymphoma, and need prompt treatment.

Last updated Nov 9, 2026

What it is

It is more common in older people and people with weakened immune systems.

Treatment depends on the type and may include monitoring, chemotherapy, immunotherapy, radiotherapy, targeted medicines, CAR-T cell therapy or a stem cell transplant.

Common signs

  • A painless swelling in the neck, armpit or groin
  • Night sweats
  • Unexplained weight loss
  • High temperature
  • Tiredness

How it is usually diagnosed

  • Lymph node biopsy
  • Blood tests
  • CT and PET-CT scans
  • Bone marrow biopsy, sometimes

Records worth keeping

Keeping these together makes each appointment easier, especially when you see a new doctor:

  • Biopsy and histology reports
  • Scan reports, including staging
  • Blood test results
  • Treatment summaries and follow-up letters

Questions to ask your doctor

  • Which type of lymphoma is it, and is it slow or fast-growing?
  • Do I need treatment now?
  • What signs should I report between appointments?

When to get help right away

Call 112 or go to the nearest emergency department if you have:

  • High fever or feeling very unwell during treatment: call your cancer care team or 112 straight away

This page is general information. It is not a diagnosis and does not replace a doctor who knows your history. Medfold keeps your records organised; it does not interpret them.

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