Multiple system atrophy

Also called MSA or Shy-Drager syndrome

Multiple system atrophy (MSA) is a rare condition where parts of the nervous system gradually stop working properly. It affects balance and movement, and the automatic functions of the body, such as blood pressure, bladder control and sweating. It usually starts in people in their 50s or 60s and can look like Parkinson's disease at first.

Last updated Nov 9, 2026

What it is

It gets worse over several years. There is no cure.

Medicines, physiotherapy, speech therapy and help with blood pressure and bladder problems can make life easier.

Common signs

  • Slowness, stiffness and tremor
  • Problems with balance and coordination
  • Dizziness or fainting on standing
  • Bladder problems
  • Erectile dysfunction
  • Slurred speech

How it is usually diagnosed

  • Examination by a neurologist
  • Blood pressure tests lying and standing
  • MRI scan
  • Bladder tests

Records worth keeping

Keeping these together makes each appointment easier, especially when you see a new doctor:

  • Neurology letters
  • Blood pressure readings lying and standing
  • MRI reports
  • Therapy and care plans

Questions to ask your doctor

  • How can my dizziness on standing be managed?
  • What support is available as things change?
  • Which therapies could help my speech and swallowing?

When to get help right away

Call 112 or go to the nearest emergency department if you have:

  • Choking, noisy breathing at night that is new or getting worse, or a fall with injury: get urgent medical help

This page is general information. It is not a diagnosis and does not replace a doctor who knows your history. Medfold keeps your records organised; it does not interpret them.

Sources