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Gilbert's syndrome

Also called Gilbert syndrome

Gilbert's syndrome is a common, harmless condition that runs in families. The liver processes a substance called bilirubin more slowly than usual, so it can build up in the blood. Many people never notice it, and it is often found by chance in a blood test.

Last updated Nov 9, 2026

What it is

It does not damage the liver and does not need treatment.

Yellowing may appear during illness, stress, fasting or after hard exercise. It is worth telling doctors you have it, as it can affect how some medicines are processed.

Common signs

  • Often no symptoms
  • Mild yellowing of the skin or whites of the eyes from time to time

How it is usually diagnosed

  • Blood tests, including bilirubin and liver function
  • Genetic test, sometimes

Records worth keeping

Keeping these together makes each appointment easier, especially when you see a new doctor:

  • Liver function test results
  • A note of the diagnosis to show other doctors

Questions to ask your doctor

  • Do I need any follow-up tests?
  • Could it affect any medicines I take?
  • Should my family be tested?

When to get help right away

Call 112 or go to the nearest emergency department if you have:

  • Yellow skin with dark pee, tummy pain or fever: get it checked, it may be something other than Gilbert's syndrome

This page is general information. It is not a diagnosis and does not replace a doctor who knows your history. Medfold keeps your records organised; it does not interpret them.

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