Complex regional pain syndrome

Also called CRPS, Reflex sympathetic dystrophy, or Sudeck's atrophy

Complex regional pain syndrome causes persistent, severe and often burning pain, usually in one arm or leg. It often develops after an injury, such as a broken wrist, or after surgery, but the pain is much worse and lasts longer than expected. The skin may also change in colour, temperature and texture.

Last updated Nov 9, 2026

What it is

The cause is not fully understood; the nervous system seems to over-respond after an injury. Many people improve over time, especially with early treatment.

Treatment combines physiotherapy and occupational therapy to keep the limb moving, pain medicines, and psychological support. Specialist pain clinics can help.

Common signs

  • Burning, stabbing or throbbing pain
  • Sensitivity to touch, even clothing
  • Swelling and stiffness
  • Changes in skin colour, temperature or sweating
  • Changes in hair and nail growth

How it is usually diagnosed

  • Diagnosed from symptoms and examination using set criteria
  • Tests to rule out other conditions

Records worth keeping

Keeping these together makes each appointment easier, especially when you see a new doctor:

  • Pain clinic letters
  • Physiotherapy and occupational therapy plans
  • Photos showing skin changes
  • A list of medicines tried

Questions to ask your doctor

  • What treatments can I try?
  • Can I be referred to a pain clinic?
  • How can I keep using the limb without making it worse?

When to get help right away

Call 112 or go to the nearest emergency department if you have:

  • Thoughts of suicide due to pain: call 112

This page is general information. It is not a diagnosis and does not replace a doctor who knows your history. Medfold keeps your records organised; it does not interpret them.

Sources