Chronic kidney disease

Also called CKD, Kidney disease, or Chronic renal failure

Chronic kidney disease is a long-term condition in which the kidneys gradually stop working as well as they should. It is common, especially with age, and mild CKD usually causes no symptoms. It is often found through blood and urine tests done for diabetes or high blood pressure, which are its two main causes.

Last updated Nov 9, 2026

What it is

CKD is graded in stages by eGFR, a blood test measure of kidney filtering, and by the amount of protein in the urine (ACR). Most people with early stages never need dialysis.

Controlling blood pressure and blood sugar, stopping smoking and some medicines can slow it down. CKD also raises the risk of heart disease, so this is checked too. A few people eventually need dialysis or a transplant.

Common signs

  • Usually none in the early stages
  • Tiredness
  • Swollen ankles, feet or hands
  • Shortness of breath
  • Itchy skin and needing to pee more often at night in later stages

How it is usually diagnosed

  • Blood test for eGFR and creatinine
  • Urine test for protein (albumin to creatinine ratio, ACR)
  • Kidney ultrasound
  • Kidney biopsy occasionally

Records worth keeping

Keeping these together makes each appointment easier, especially when you see a new doctor:

  • eGFR, creatinine and ACR results over time
  • Blood pressure readings
  • Kidney ultrasound reports
  • Your list of medicines, including ones to avoid such as some painkillers

Questions to ask your doctor

  • What stage is my CKD, and is it changing?
  • What can I do to protect my kidneys?
  • Which medicines should I avoid?

When to get help right away

Call 112 or go to the nearest emergency department if you have:

  • Peeing much less or not at all, severe breathlessness or chest pain: call 112

This page is general information. It is not a diagnosis and does not replace a doctor who knows your history. Medfold keeps your records organised; it does not interpret them.

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