Acute myeloid leukaemia

Also called AML or Acute myeloid leukemia

Acute myeloid leukaemia is a cancer in which the bone marrow produces large numbers of abnormal immature cells of the myeloid line. They stop the marrow making enough healthy red cells, white cells and platelets. It develops over weeks and is treated urgently by haematology teams.

Last updated Nov 9, 2026

What it is

It is more common with age. Previous chemotherapy or radiotherapy, some blood disorders and smoking increase the risk.

Treatment depends on the type of AML and on general health: intensive chemotherapy, gentler treatments, targeted medicines, and sometimes a stem cell transplant.

Common signs

  • Tiredness, pale skin and breathlessness
  • Frequent infections and fevers
  • Bruising and bleeding easily
  • Bone pain and weight loss

How it is usually diagnosed

  • A full blood count and blood film
  • A bone marrow biopsy with genetic tests, which guide treatment

Records worth keeping

Keeping these together makes each appointment easier, especially when you see a new doctor:

  • Blood counts throughout treatment
  • Bone marrow and genetic reports
  • Treatment plan and the dates of each cycle
  • Transfusion records and discharge letters

Questions to ask your doctor

  • What are the genetic features of my AML, and how do they affect treatment?
  • What are my treatment options, and what are their aims?
  • What should I do if I get a fever at home?

When to get help right away

Call 112 or go to the nearest emergency department if you have:

  • A temperature of 38°C or more during treatment (call your treatment team immediately)
  • Bleeding that will not stop
  • Breathlessness or confusion

This page is general information. It is not a diagnosis and does not replace a doctor who knows your history. Medfold keeps your records organised; it does not interpret them.

Sources